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CVE-2026-31967

27
FAUCET Score

CVE-2026-31967 is a critical vulnerability (CVSS 9.1) in HTSlib, a library used for bioinformatics file formats, specifically impacting the `cram_decode_slice()` function. This out-of-bounds read (CWE-125) occurs due to unvalidated mate reference IDs in CRAM records, allowing a remote attacker to trigger information leakage or cause a program crash. The attack vector is network-based with low complexity, requiring no privileges or user interaction. Despite its high severity, there is currently no evidence of active exploitation, public exploit code, or significant community discussion surrounding this vulnerability. Organizations using HTSlib should update to versions 1.23.1, 1.22.2, or 1.21.1 to mitigate this risk.

Impacted Technologies

VendorProductVersion(s)CPE
< 1.21.1CPE matchmatch criteria
cpe:2.3:a:htslib:htslib:*:*:*:*:*:*:*:*
>= 1.22, < 1.22.2CPE matchmatch criteria
cpe:2.3:a:htslib:htslib:*:*:*:*:*:*:*:*
1.23CPE matchmatch criteria
cpe:2.3:a:htslib:htslib:1.23:*:*:*:*:*:*:*

CVSS Data

CVSS version used by this source: 4.0

6.9MEDIUM

CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X

Attack Vector
NETWORK
Attack Complexity
LOW
Attack Requirements
NONE
Privileges Required
NONE
User Interaction
NONE
VS Confidentiality
LOW
VS Integrity
NONE
VS Availability
LOW
SS Confidentiality
NONE
SS Integrity
NONE
SS Availability
NONE
Exploit Maturity
NOT_DEFINED
CvssVersion
4.0

Exploit Intelligence

EPSS Score
0.45%
Probability of exploitation in next 30 days
EPSS Percentile
36.3%
Percentile rank of EPSS score among Peer Group
As of 2026-07-27
Model: v2026.06.15
This CVE's current EPSS score of 0.0044 is in the 14th percentile among its peer group of 36,862 CVEs.

Social Chatter

The average CVE in this peer group has 0.0 Twitter, 0.1 Reddit, 0.3 Bluesky, 0.3 Mastodon, and 2.4 GitHub mentions.

Media Mentions

No media coverage found for this CVE.

The average CVE in this peer group has 0.3 InfoSec Media, 0.0 Vendor Blog, and 0.0 Security Researcher mentions.

Remediation

Remediation records are not available for this CVE.

References

github.com / samtools/htslib/commit/9cefb46453ad471e933b8212d4f45920524d3357
Patch
github.com / samtools/htslib/security/advisories/GHSA-33x5-c6vj-8f2w
PatchVendor Advisory