CVE-2026-31966 is a critical out-of-bounds read vulnerability in the HTSlib bioinformatics library, specifically affecting the `cram_decode_seq()` function when processing CRAM files. This flaw allows an attacker to remotely leak arbitrary data, including program state, or cause a program crash due to insufficient validation of feature data series. Rated 9.1 CRITICAL (CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:N/A:H), it can be exploited with low complexity and no user interaction. There is currently no evidence of active exploitation, public exploit code, or significant community discussion regarding this vulnerability. Organizations using HTSlib versions prior to 1.23.1, 1.22.2, or 1.21.1 should update immediately as there is no workaround.
| Vendor | Product | Version(s) | CPE |
|---|---|---|---|
< 1.21.1CPE matchmatch criteria | cpe:2.3:a:htslib:htslib:*:*:*:*:*:*:*:* | ||
>= 1.22, < 1.22.2CPE matchmatch criteria | cpe:2.3:a:htslib:htslib:*:*:*:*:*:*:*:* | ||
1.23CPE matchmatch criteria | cpe:2.3:a:htslib:htslib:1.23:*:*:*:*:*:*:* |
CVSS version used by this source: 4.0
CVSS:4.0/AV:N/AC:L/AT:N/PR:N/UI:N/VC:L/VI:N/VA:L/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X
The average CVE in this peer group has 0.0 Twitter, 0.1 Reddit, 0.3 Bluesky, 0.3 Mastodon, and 2.4 GitHub mentions.
No media coverage found for this CVE.
The average CVE in this peer group has 0.3 InfoSec Media, 0.0 Vendor Blog, and 0.0 Security Researcher mentions.
Remediation records are not available for this CVE.